Current Funding

ORF-GL2-01-003-Ministry of Research and Innovation, Ontario Research Fund
2009/05/04-2013/03/31
Scott Tanner (PI)
Mass cytometry is a transformational new technology, developed in Ontario, which allows the identification and investigation of rare, diseased cells. An international team of experts from academia and industry will evaluate and optimize the new technology, and create diagnostic and therapeutic applications.

Health Technology Exchange Grant with support from DVS Sciences Inc.
2009/10/28-2011/06/30
Vladimir Baranov (PI)
"High Efficiency Rare Cell Injector for Multiplexed Mass Cytometry"
This project is dedicated to development of a novel technology of the Sample Introduction System to inject one cell or bead at a time into the Mass Cytometer - an innovative cell analysis instrument for massively multi-parametric cytometry with atomic mass spectrometry detection.

CIRM-CSCC (California Institute of Regenerative Medicine/Cancer Stem Cell Consortium) Disease Team Award-University Health Network
John Dick (PI)
"Development of Highly Active Active Anti-Leukemia Stem Cell Therapy"
Genomic and proteomic analyses will address disease heterogeneity and will identify signatures that will be used to prospectively predict responses in patients in planned IND-supported clinical trials. Because cellular and molecular responses can be readily and rapidly assessed at the stem cell level in blood and marrow of patients, we are poised to establish a new paradigm for translation of stem cell research into new treatments for many types of cancer.

National Institute of Health (NIH) IMAT-Exploratory Development Grant
2009/05/01 - 2012/04/30
Scott Tanner (PI)
"Development of (Prototype) Bead Array Flow Cytometer with Mass Spectrometer Detection"

Completed Research Support

National Institute of Health (NIH) R01 Grant
2006-2010
Mitch Winnik (PI)
"Metal tagging of bioactive molecules for prognostic assays coupled with ICP-MS."
The specific aim of this project was to develop an optimized tagging kit to facilitate inductively coupled mass spectrometric (ICP-MS) detection using standard affinity-based-biological assays. This goal would allow the sensitivity, resolution, and multiplexing potential of ICP-MS to be used in biological assays.

Genome Canada-GC Tech Development Grant
2008/04/01-2010/03/31
Scott Tanner (PI)
"Massively Multiparametric Flow Cytometer Analyzer"
The central objective of this Genome Canada Technology Development (GC-TD) project has been to develop and refine novel technology consisting of a mass spectrometer-based flow cytometer and a set of element-tagged affinity reagents.