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Yingfu Li, PhD
Associate Professor and Canada Research Chair in
Directed Evolution of
Nucleic Acids
Department of Biochemistry and Biomedical Sciences and Department of Chemistry
McMaster University |
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- Research
- People
- Publications
- Li Lab
Shen Y, Chiuman W, Brennan JD, Li Y. Catalysis and rational engineering of trans-acting pH6DZ1, an RNA-cleaving and fluorescence-signaling deoxyribozyme with a four-way junction structure. Chembiochem. 2006 Sep;7(9):1343-8.
Elowe NH, Nutiu R, Allali-Hassani A, Cechetto JD, Hughes DW, Li Y, Brown ED. Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity. Angew Chem Int Ed Engl. 2006 Aug 25;45(34):5648-52.
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“If cancer stem cells lie at the heart of some cancers, then being able to predict the behavior of tumors and providing effective therapies against them means understanding the abnormal growth pathways within the stem cells themselves.”
- John Dick, Project Leader (UHN)
“The only reason that I'm willing to take a risk on this project is my confidence in the quality and camaraderie of my colleagues.”
- Scott Tanner, Principal Investigator (University of Toronto)
“We're examining DNA not for its well-recognized role as the genetic material to store and transmit genetic information, but rather for its less-known potential to act as a novel cancer diagnostic tool.”
- Yingfu Li, Principal Investigator (McMaster University)
“We're gaining more understanding of cell defects and how to modify them, so that treatment is no longer a shotgun approach, but more like an arrow aimed at a specific target.”
- Mark Minden, Principal Investigator (OCI)
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Front row:
Left to right: Naveen Kumar (PDF), Zhanxu Jia (PDF), Yingfu Li (PI), Lieven Billen (GS), Johanna Withers (US), Laura Jasmin (US), Jasmine Yu (US), Xinyi Zhou (US).
Back row:
Left to right: Jeffery Lam (US), Sri Kandadai (PDF), Razvan Nutiu (GS), William Chiuman (GS), Ken Schlosser (GS), Yutu Shen (GS)
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